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EmbryoGlue
EmbryoGlue is a substance that is used in the final stage of IVF treatment to help maximise the chance of fertility success.
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What is EmbryoGlue?
EmbryoGlue is made of a substance called hyaluronan, which is used to improve the chance of success of an individual undergoing fertility treatment. There are no risks associated with using EmbryoGlue, and it can be recommended to individuals who have had previous unsuccessful IVF treatments.
It is used during an embryo transfer, which is the final phase of IVF (in vitro fertilisation treatment). EmbryoGlue aims to help the embryo implant, which is an important stage of IVF treatment.
How much is EmbryoGlue?
If you want to use embryo glue, you will need to notify the team. This add-on is not included with NHS cycles, but may be part of some treatment packages.
How does EmbryoGlue work?
EmbryoGlue helps bridge the embryo and womb together, allowing the implantation to work.
The high concentration of hyaluronan is thought to protect the embryo and help it bind and implant to the lining of the womb.
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Evidence and regulations
According to the Human Fertilisation and Embryology Authority, the use of hyaluronate enriched pre-transfer culture medium, like EmbryoGlue, has been rated as an amber add-on treatment. This means that some studies have shown that it is effective, and some have shown that it is not. Â
A Cochrane analysis of available trial evidence conducted in 2020 showed that using hyaluronic acid in embryo transfer media does increase the chance of clinical pregnancy and live birth.
Learn more about our treatments
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Dr James Hopkisson
Medical Director, TFP Nurture Fertility · Reviewed 7 September 2026
Demonstrated Experience
- ·Over 30 years of dedicated experience in fertility and IVF.
- ·Laparoscopic surgeon who specialises in correcting pelvic adhesions, uterine fibroids, and advanced endometriosis to enhance natural and assisted conception.
- ·Lead for subspecialty training in reproductive medicine in Nottingham, responsible for training the next generation of specialist doctors in fertility.
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Ready to start your fertility journey? We're here for you
Speak to our patient support team for advice about your options and to book your first consultation with a fertility expert.