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Genetic screening

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Pre-implantation genetic screening (PGS)

Chromosomal abnormality is one of the most common causes of unsuccessful pregnancy. If an embryo has too many or too few chromosomes (a condition called aneuploidy), this can have a serious effect on its chances of developing normally into a fetus and then a baby. In many cases, embryos with the wrong number of chromosomes stop growing by themselves, and this unfortunately often results in miscarriage.

This is no less common with IVF treatment. However, the IVF process enables us to monitor the development of multiple embryos at the same time. We can provide various levels of genetic screening during treatment, to help us select embryos with normal chromosomes that will have the best chance of developing into a healthy pregnancy.

The pre-implantation genetic screening we offer is Next Generation Sequencing from embryo biopsy.

How does PGS work?

The first few stages of an IVF cycle that involves PGS are no different from any other.

The embryos that develop will be examined and you will be advised if they are suitable for a biopsy on day five or six. A small sample of cells (called a biopsy) within the embryo are taken using a needle. We make sure that we take this from the cells which will go on to make the placenta so that we do not damage the cells that will make the baby. The biopsy samples are placed in tubes and sent to the genetics laboratory. The genetic test takes four weeks to process, so your embryos are frozen until we have the result.

Scientists working in the laboratory carry out the PGS test on all of the samples received. The test results indicate how many copies there are of each chromosome, revealing any abnormal embryos. PGS does not require additional blood tests prior to the IVF cycle. Once the results are known, your follow up appointment will be confirmed.

How much does Pre-implantation genetic testing (PGT) cost?

Our price list is structured in sections to give you a clear view of the potential steps in your treatment and the associated costs, to allow you to make informed financial planning.

Where is Pre-implantation genetic screening (PGS) and Pre-implantation genetic testing (PGT) available?

Genetic screening is available in UK TFP clinics through a link with Reprogenetics in TFP Oxford Fertility. If you’d like to discuss the genetic diagnosis options available to you for your IVF cycle, please contact us.

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