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Treatments

PGT-A

Preimplantation genetic testing for aneuploidy (PGT-A) checks for abnormal numbers of chromosomes in embryos. It helps our expert embryologists choose the best embryos for IVF treatment and reduce the chances of miscarriage.

With over 35 years of experience, our fertility specialists and embryologists use the latest technologies and fertility treatments to give you the best chance of success.

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What is PGT-A?

Pre-implantation genetic testing (PGT) is a test for embryos to check for genetic or chromosomal issues before they’re used in IVF treatment.

PGT-A (previously known as pre-implantation genetic screening or PGS) tests for abnormal numbers of chromosomes in embryos created during IVF or ICSI.

Chromosomes are the packages of DNA within the cells of our body. Normally, there are 46 chromosomes in each cell. When the number of chromosomes doesn’t equal 46, this is known as aneuploidy.

Aneuploidy in an embryo is one of the main causes of miscarriage or IVF failure, particularly in older patients. It also causes conditions such as Down’s Syndrome.

This test may be a good option for you if:

  • You’re an older woman

  • You’ve had multiple miscarriages or failed IVF cycles before

PGT-A testing success rates

Research has shown that PGT-A can reduce the time taken to achieve a pregnancy if one is to be achieved by avoiding the transfer of abnormal embryos.

PGT-A has also been found to reduce the chance of miscarriage.

It should be noted that the HFEA (the UK fertility regulator) advises that PGT-A is a red flag rated add-on test as it does not increase the chance of pregnancy.

The test may show that no healthy embryos are available to continue the IVF treatment cycle.

Your fertility consultant will discuss your particular case with you to help you decide if PGT-A testing is right for you.

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Madeline children

Madeline's story

“Unlike many of my friend’s clinics, where treatments and add-ons are pushed, the team very much had our overall wellbeing in mind.”

Fertility counselling and support

As part of your personalised treatment plan with us, you’ll have access to a fertility counsellor.

They can help you decide what’s right for you and what to expect from your treatment journey.

For IVF with PGT-A, a genetic counselling service is available at no extra cost.

We’re here to reassure you, answer your questions, and give you the emotional support you need every step of the way.

How much does PGT-A testing cost?

Our price list aims to give you a clear view of the cost of PGT and the associated costs, to allow you to make informed financial planning.

Read about ways to pay for your treatment.

Work up and genetic counselling

Non-refundable; Includes DNA reference collection and development of unique test that lasts for 2 years

PGT-A

No charge

PGT-A

Pre-implantation genetic testing for aneuploidies (PGT-A) Includes biopsy and testing and excludes production, freezing, storage and transfer of embryos (see below for cycle charges).

1 embryo

£770

2 embryos

£1,320

3 embryos

£1,870

4 embryos

£2,310

5 embryos

£2,750

6 embryos

£3,190

Additional Analysis (per embryo)

£385

Cycle packages

To create the embryos for testing and to transfer embryos once screened.

TFP Freeze - all and Transfer Cycle

Please see main clinic pricelist

TFP Frozen Embryo Transfer Cycle

Please see main clinic pricelist

Thaw and refreeze

For patients who undertake genetic testing after their embryos have been frozen. Includes thaw and re-freeze of embryo(s) to be tested.

Thaw and refreeze per embryo

£250

FAQs

What’s the difference between PGT-A and PGT-M?

While PGT-A tests for an abnormal number of chromosomes in the embryo, PGT-M tests for specific genetic disorders caused by mutations in a single gene.

PGT-M is used if one or both parents are at risk of passing on a genetic condition to their baby.

TFP Oxford Fertility is a selected IVF units that provides NHS England-funded PGT-M treatment.

Learn more about PGT-M

How long do PGT-A results take?

It will take roughly four weeks from the day of testing of your embryos to receive the PGT-A results.

It’s an additional step during IVF treatment after the fertilisation stage and before embryo transfer to the womb.

After fertilisation, one of our experienced embryologists carefully performs a biopsy on each blastocyst (an embryo that has grown into a ball of cells) to take a sample of cells.

The sample is tested at a specialist laboratory to complete to the highest standards.

The embryos are frozen after biopsy while the test is carried out.

Embryos that have a normal number of chromosomes will be chosen for transfer to continue your IVF cycle.

Can PGT-A test for Down’s Syndrome?

PGT-A can test for Down’s Syndrome and other conditions caused by aneuploidy – having more or fewer chromosomes than normal.

Can you do PGT-A on frozen embryos?

Yes, we can perform PGT-A using embryos that have been frozen already.

Our embryologists will gently thaw your embryos to perform the biopsy needed to collect a sample of cells for testing.

The embryos are then carefully refrozen using our advance vitrification freezing technique to minimise the risk of damage while the test is carried out.

How accurate is PGT-A testing?

Modern PGT-A testing techniques are accurate, but there is a small chance that the test might give the wrong result.

This can mean healthy embryos are discarded.

We work with a specialist lab for PGT-A who use the latest equipment and evidence-based techniques to minimise these risks.

There’s also a chance that the cells tested have a mix of abnormal and regular chromosome numbers.

This is called a mosaic embryo.

Mosaic embryos may have a higher chance of miscarriage but can also result in a healthy live birth.

Does PGT-A test for autism?

No, PGT-A cannot test for autism.

Although the exact causes are unclear, autism is not caused by an abnormal number of chromosomes, which this test is for.

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