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Implantation support

Implantation irrigation or seminal plasma injection

The implantation of the embryo into the uterus of the mother is a very complex process. In order to avoid rejection of the embryo, an immune tolerance against the embryo must develop. The seminal plasma (ejaculate without sperm) appears to have an active role to play in this process. The implantation of an embryo requires a complex interplay of the messengers of seminal plasma, the cells of the uterus and the immune system.


The seminal plasma conditions the mother's immune response and causes an immune tolerance to the embryo. The seminal plasma also causes molecular and cellular changes in the lining of the uterus necessary for embryo implantation and development.


The seminal plasma thus has a crucial role in the preparation of the uterus for the embryo and probably in the implantation of the embryo as well as the formation of a stable and healthy pregnancy.

What is seminal plasma?


The seminal plasma (ejaculate without sperm) is mainly made up of the secretion from the seminal vesicale and 25% secretion from the prostate gland.


The seminal plasma also contains a variety of messenger substances such as interleukin and TGF. Its purpose is the growth of blood vessels and the promotion of inflammation. It also influences immunological reactions.

Implantation support process

If, in the course of fertility treatment, it turns out that implantation support will increase your chances of pregnancy, the procedure is usually as follows:

  • Sperm sample: The man collects sperm through masturbation and delivers it to the laboratory of the fertility clinic.

  • Centrifugation: The sperm are separated from the plasma in a centrifuge. About 0.1 or 0.5 ml of this so-called seminal plasma is taken with a syringe.

  • Seminal plasma injection: After the egg collection from the woman or after the embryo transfer, the seminal plasma is carefully injected into the cervix.


Let us advise you

The doctors at our fertility clinics in Vienna, Wels and Klagenfurt will be happy to answer any questions you may have about implantation therapy. Should you fail to become pregnant despite good conditions for pregnancy, we will discuss with you in detail whether this procedure should also be included in your treatment plan. Of course, we will go through all the steps with you in detail and inform you about the costs and possible risks of the treatment.


Contact your preferred clinic now - we look forward to hearing from you!

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