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Double test

Biochemical tests

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The double test is a non-invasive prenatal test, safe for both mother and child. It involves the determination of biochemical parameters in maternal blood. Correlation of concentrations of tested compounds, in conjunction with medical history and ultrasound image, allows us to assess the risk of chromosomal defects in the fetus.


The vast majority of pregnant women are in the low-risk group. Patients in the high-risk group can undergo further examinations (invasive diagnostic tests): amniocentesis, chorionic villus biopsy and cordocentesis, which are always performed by a highly qualified specialist.


The double test is performed between 11-13 weeks of pregnancy. It includes a determination of the level of PAPP-A protein (plasma pregnancy protein A) and the free subunit of chorionic gonadotropin (β-HCG). It allows us to assess the risk of chromosomal defects in the fetus, including Down syndrome (trisomy 21), Edwards syndrome (trisomy 18) and Pateau syndrome (trisomy 13). If you are interested in undergoing this test, talk to your doctor at TFP.

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