The diagnostic methods are individually adapted to couples wishing to have children. In order to choose the right types of fertility tests for you, we conduct a detailed interview, because both of your medical histories play an important role.
Changes in the menstrual cycle, how long you've been trying to conceive naturally, previous operations, or illnesses are also decisive factors. Couples struggling to conceive can start thinking about which points might be important for the fertility clinic in advance. The age of the woman is a decisive characteristic because, from the age of 30, the quality of the ova continuously decreases. In men, on the other hand, it must be clarified whether the sperm quality is still sufficient or to what extent it’s limited.
The AMH value is an indicator for the ovaries stimulation capacity and ovarian activity.
Cycle monitoring is when a couple is being prepared for “sexual intercourse at the optimal time”. With this method, it is important that the fallopian tubes are unobstructed and fully operational and that semen quality is normal. This preliminary treatment measure is also referred to as a fertility check. The woman’s cycle is monitored with specific ultrasound and hormone tests. This makes it possible to monitor the number, size and maturity of the follicles.
If damages or any changes to the fallopian tubes are suspected, imaging examination procedures can also be applied. Imaging procedures used may be the Hysterosalpingogram (HSG) and the Hysterosalpingo-Contrast-Sonography (usually shortened to HyCoSy).
A Hysteroscopy is performed to determine uterine malformations, fibroids or alterations of the endometrium.
A sperm analysis is often the first step in the diagnostic stage of fertility treatment. Through a microscopic examination in our laboratories, we examine and assess the number of sperm cells per millilitre of semen, the shape of the sperm and their motility. If less than 15 percent of the sperm is regular in shape and less than 25 percent have normal motility, natural pregnancy is unlikely.
With the DNA diagnostic method SpermFit, we determine the degree of fragmentation in the sperm DNA. The higher it turns out to be, the less likely it is that a pregnancy will occur naturally.
Genetic disorders often impair fertility. If a pregnancy nevertheless occurs, the child may develop illnesses that lead to considerable restrictions in physical and mental health. We see it as our task in the TFP clinics to provide affected couples with honest and comprehensive information about problems and risks and, if necessary, to support them in making individual decisions. Each couple comes to our clinics with their own values and convictions.
If a patient has already undergone several unsuccessful attempts at implantation, or has suffered repeated miscarriages, without there being any other obvious causes, our doctors in the TFP clinic recommend the woman undergo immunological testing. This involves a piece of the uterine lining being biopsied between the 19th and 21st days of the cycle and then tested with respect to its concentration of NK cells and plasma cells in a specialist laboratory.
There is only a short space of time in which an embryo is able to successfully implant in the uterine lining (endometrium). The build-up of the uterine lining over the course of one's cycle is hormonally controlled for the most part. When exactly the uterine lining is ready for implantation of the fertilised egg differs from woman to woman. The ERA procedure (endometrial receptivity array) examines a group of 238 genes in the uterine lining. The state of these genes provides information about the receptivity of the mucosa, i.e., its ability to facilitate successful implantation, on the day of the test.
Trophectoderm biopsy (TEB) is one of the possible tests that can be done for couples wanting children, where there is a suspicion that both sides could pass on a genetic defect that could result either in miscarriage or stillbirth, or the embryo having a severe genetic disease. It involves a biopsy of those cells of the embryo which develop into the placenta – that is, the "trophectoderm" or "trophoblast cells".
With the help of a 3D ultrasound, it is now possible to obtain photorealistic images and surface representations of follicles during stimulation. In the 3D process the depth is recorded, so that, for example, the volume of an organ is recognizable. The 3D ultrasound allows a precise spatial representation. This allows failures to be diagnosed even more successfully. The recorded 3D volumes are stored, so that after the actual investigation it is still possible to edit the images in order to obtain the best diagnostic result.